Differences in cardiovascular risk profile of diabetic subjects discordantly classified by diagnostic criteria based on glycated hemoglobin and oral glucose tolerance test Running title: A1C vs OGTT for diabetes diagnosis
نویسندگان
چکیده
Mauro Boronat, PhD, Pedro Saavedra, PhD, Laura López-Ríos, PhD, Marta Riaño, MD, Ana M. Wägner, PhD, Francisco J. Nóvoa, PhD. Section of Endocrinology and Nutrition, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain, Department of Medical and Surgical Sciences, Las Palmas University, Spain, Mathematics Department, Las Palmas University, Spain, Service of Biochemistry, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain.
منابع مشابه
Differences in Cardiovascular Risk Profile of Diabetic Subjects Discordantly Classified by Diagnostic Criteria Based on Glycated Hemoglobin and Oral Glucose Tolerance Test
OBJECTIVE To characterize the cardiovascular risk profile of subjects categorized differently by A1C- and oral glucose tolerance test (OGTT)-based diagnostic criteria for diabetes according to the recommendations of the American Diabetes Association (ADA). RESEARCH DESIGN AND METHODS An OGTT, A1C, and several cardiovascular risk factors were assessed in 964 individuals without known diabetes ...
متن کاملResponse to Comment on: Boronat et al. Differences in Cardiovascular Risk Profile of Diabetic Subjects Discordantly Classified by Diagnostic Criteria Based on Glycated Hemoglobin and Oral Glucose Tolerance Test. Diabetes Care 2010;33:2671–2673
We appreciate the efforts of Kramer and Araneta (1) to investigate whether our findings are reproducible in the Rancho Bernardo cohort. In apparent contrast to our results (2), they observed that subjects with diabetic oral glucose tolerance test (OGTT) but A1C ,6.5% displayed a more unfavorable cardiovascular risk profile than subjects with A1C $6.5% (1). However, as noted by the authors, grou...
متن کاملComment on: Boronat et al. Differences in Cardiovascular Risk Profile of Diabetic Subjects Discordantly Classified by Diagnostic Criteria Based on Glycated Hemoglobin and Oral Glucose Tolerance Test. Diabetes Care 2010;33:2671–2673
We read with interest the article by Boronat et al. (1). In that article, individuals with discordant diabetes status by A1C and oral glucose tolerance test (OGTT) had their cardiovascular risk profile evaluated. Those who fulfilled the A1C-based criterion presented greater measures of BMI and waist circumference and lower values for HDL cholesterol than individuals with diabetic OGTT but A1C,6...
متن کاملUse of Glycated Hemoglobin in the Diagnosis of Diabetes Mellitus and Pre-diabetes and Role of Fasting Plasma Glucose, Oral Glucose Tolerance Test
BACKGROUND A highly standardized screening test for newly diagnosis diabetes and pre-diabetes is necessary. the study goal was to clarify the power and efficacy of glycated hemoglobin (HbA1c) in the diagnosis of diabetes and pre-diabetes by comparing against the other American Diabetes Association (ADA) diagnostic criteria of fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT). ...
متن کاملThe 1997 American Diabetes Association criteria versus the 1985 World Health Organization criteria for the diagnosis of abnormal glucose tolerance: poor agreement in the Hoorn Study.
OBJECTIVE Recently, the American Diabetes Association (ADA) introduced new diagnostic criteria. These new criteria are based on fasting plasma glucose levels, avoiding the burdensome oral glucose tolerance test (OGTT). We compared the 1997 ADA criteria with the 1985 World Health Organization (WHO) criteria with respect to the prevalence of diabetes and the cardiovascular risk profile in the pop...
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